4366-18-1
4366-18-1 結構式
基本信息
中文別名
庫美香豆素庫美香豆素,雙香豆素醚
英文別名
Ph 137Cumetarol
Cumetharol
coumetarol
Dicumoxane
Dicoumoxyl
Cumethoxethan
3,3'-(2-Methoxyethylidene)bis(4-hydroxycoumarin)
2H-1-Benzopyran-2-one, 3,3'-(2-methoxyethylidene)bis[4-hydroxy-
2-hydroxy-3-[1-(2-hydroxy-4-keto-chromen-3-yl)-2-methoxy-ethyl]chromone
物理化學性質(zhì)
熔點156-157°
沸點639.9±55.0 °C(Predicted)
密度1.514±0.06 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)4.20±1.00(Predicted)
形態(tài)Solid
顏色White to off-white
庫美香豆素價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/05/22 | HY-U00017 | 庫美香豆素 Coumetarol | 4366-18-1 | 5 mg | 810元 |
| 2025/05/22 | HY-U00017 | 庫美香豆素 Coumetarol | 4366-18-1 | 10 mM * 1 mLin DMSO | 891元 |
| 2025/05/22 | HY-U00017 | 庫美香豆素 Coumetarol | 4366-18-1 | 10 mg | 1350元 |
常見問題列表
生物活性
Coumetarol (Dicumoxane) 是維生素 K 拮抗劑。靶點
vitamin K
體外研究
Coumetarol (Dicumoxane), an oral anticoagulant, is active in both models. The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model. Treatment with the vitamin K antagonist Coumetarol in a dose of 25 mg/kg p.o. twice daily for 2 days results in a significant reduction in thrombus weight by 50% in the venous stasis model and by 75% in the arterio-venous shunt model. In both experiments the coagulation time as measured by the Thrombotest is prolonged to the same extent.