384361-79-9
中文名稱
化合物 T28193
英文名稱
2-chloro-N-[[4-(dimethylamino)phenyl]methyl]-N-[3-phenyl-3-(4-propan-2-yloxyphenyl)propyl]acetamide
CAS
384361-79-9
分子式
C29H35ClN2O2
分子量
479.05
MOL 文件
384361-79-9.mol
384361-79-9 結(jié)構(gòu)式
基本信息
中文別名
化合物 T28193 英文別名
2-chloro-N-[[4-(dimethylamino)phenyl]methyl]-N-[3-phenyl-3-(4-propan-2-yloxyphenyl)propyl]acetamide物理化學(xué)性質(zhì)
沸點(diǎn)631.8±55.0 °C(Predicted)
密度1.129±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)4.81±0.12(Predicted)
應(yīng)用領(lǐng)域
用途一
NPD926 is an inducer of cancel cell death. NPD926 sensitized cells to inhibitors of system x(c)?, a cystine-glutamate antiporter considered to be a potential therapeutic target in cancers including cancer stem cells. Induction of excessive levels of reactive oxygen species (ROS) by small-molecule compounds has been considered a potentially effective therapeutic strategy against cancer cells, which are often subjected to chronic oxidative stress.