29876-14-0
29876-14-0 結(jié)構(gòu)式
基本信息
尼可曲朵
N-(2-(1H-吲哚-3-基)乙基)煙酰胺
Nicotredole
N-[2-(3-indolyl)ethyl]nicotinamide
N-(2-(1H-Indol-3-yl)ethyl)nicotinaMide
N-[2-(1H-indol-3-yl)ethyl]pyridine-3-carboxamide
3-Pyridinecarboxamide, N-[2-(1H-indol-3-yl)ethyl]-
物理化學(xué)性質(zhì)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/02/08 | HY-137394 | 尼可曲朵 Nicotredole | 29876-14-0 | 1 mg | 216元 |
| 2025/02/08 | HY-137394 | 尼可曲朵 Nicotredole | 29876-14-0 | 5mg | 496元 |
| 2025/02/08 | HY-137394 | 尼可曲朵 Nicotredole | 29876-14-0 | 10mg | 745元 |
常見問題列表
Nicotredole inhibits prostaglandin synthetase activity in vitro.
Nicotredole produces antiinflammatory effects in carrageenin-induced rat paw oedema.
Nicotredole reverses pyrogen-induced hyperthermia in rats, elicits analgesic effects in rats, prolongs the time of hexobarbital sleep in rats and inhibits locomotor activity in rats and mice.
Nicotredole (i.p.) has LD50s of 1260 mg/kg and 1980 mg/kg for male rats and male mice, respectively.
Nicotredole (p.o.) has LD50s of 8.5 g/kg and 9.3 g/kg for male rats and male mice, respectively.
Nicotredole (25 mg/kg; p.o. or i.p.) undergoes fast absorption (t
1/2
=4.92-17.5 min) and elimination (t
1/2
=55.72-74.52 min), can reach C
max
(11-13 μg/cm
3
) after 30 min, and gives AUC values in the range of 21.40-27.30 (μg?h/cm
3
).