225110-25-8
中文名稱(chēng)
鐮葉芹二醇
英文名稱(chēng)
Falcarindiol
CAS
225110-25-8
分子式
C17H24O2
分子量
260.37
MOL 文件
225110-25-8.mol
更新日期
2025/02/05 09:31:28
225110-25-8 結(jié)構(gòu)式
基本信息
中文別名
發(fā)卡二醇鐮葉芹二醇
英文別名
8S)-Falcarindiol(3R,8S)-Falcarindiol
(+)-(3R,8S)-falcarindiol
3(R),8(S),9(Z)-Falcarindiol
Falcarindiol/(3R),(8S)-Falcarindiol
(3R,8S,9Z)-1,9-Heptadecadiene-4,6-diyne-3,8-diol
1,9-Heptadecadiene-4,6-diyne-3,8-diol,(3R,8S,9Z)-
所屬類(lèi)別
生物化工：植物提取物物理化學(xué)性質(zhì)
沸點(diǎn)408.2±45.0 °C(Predicted)
密度1.000±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
酸度系數(shù)(pKa)11.65±0.20(Predicted)
形態(tài)Oil
應(yīng)用領(lǐng)域
用途1
用于含量測(cè)定/鑒定/藥理實(shí)驗(yàn)等。用途2
Falcarindiol was isolated as an algicidal principle against the harmful red tide dinoflagellate, Heterocapsa circularisquama, from Notopterygii Rhizoma through bioassay-guided separation.To determine
the ambiguous absolute structure of this active principle, all three stereoisomers as well as falcarindiol were synthesized. 聽(tīng)As a result of intensive analytical of their physicochemical properties, t
he configuration of Falcarinfiol was revealed to be 3R,8S. 聽(tīng)(3S,8S)- and (3S,8R)-isomers were found to exhibit more potent algicidal activity than (3R,8S)-Falcarindiol isolated from Notopterygii Rhizo
ma.鐮葉芹二醇價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/02/08 | HY-N1976 | 鐮葉芹二醇 (+)-(3R,8S)-Falcarindiol | 225110-25-8 | 1 mg | 500元 |
| 2025/02/08 | HY-N1976 | 鐮葉芹二醇 (+)-(3R,8S)-Falcarindiol | 225110-25-8 | 5 mg | 1500元 |
| 2025/02/08 | HY-N1976 | 鐮葉芹二醇 (+)-(3R,8S)-Falcarindiol | 225110-25-8 | 10 mg | 2400元 |
常見(jiàn)問(wèn)題列表
生物活性
Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) 是一種天然的聚乙炔化合物，存在于傘形科的許多植物中。Falcarindiol 可抑制LPS刺激的 inducible nitric oxide synthase (iNOS)、tumor necrosis factor alpha (TNFα)、interleukin-6 (IL-6) 和 interleukin-1 beta (IL-1β) 的表達(dá)。Falcarindiol 可減弱LPS誘導(dǎo)的 JNK、ERK、STAT1 和 STAT3 信號(hào)分子的激活。Falnidamol 是一種具有抗癌活性的嘧啶嘧啶類(lèi)化合物。