205437-64-5
中文名稱
化合物BU 224 HYDROCHLORIDE
英文名稱
BU 224 hydrochloride
CAS
205437-64-5
分子式
C12H12ClN3
分子量
233.7
MOL 文件
205437-64-5.mol
更新日期
2025/06/07 14:20:08
205437-64-5 結(jié)構(gòu)式
基本信息
中文別名
化合物BU 224 HYDROCHLORIDE 英文別名
BU 224,Tumor Necrosis Factor Receptor,inhibit,Inhibitor,BU224,Imidazoline,BU-224,TNF Receptor,Alzheimer's disease,TNFR,Apoptosis,BU 224 hydrochloride,anti-apoptotic,ACTH,antidepressant,neuroprotective,Imidazoline Receptor,5-HT,anti-inflammatory應(yīng)用領(lǐng)域
用途一
BU-224 is a Putative I2 antagonist; and a high affinity ligand for the imidazoline I2 binding site (Ki = 2.1 nM). BU224 reverses cognitive deficits, reduces microgliosis and enhances synaptic connectivity in a mouse model of Alzheimer's disease.