1835667-63-4
中文名稱
BEFOTERTINIB
英文名稱
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide
CAS
1835667-63-4
分子式
C29H32F3N7O2
更新日期
2025/04/14 11:32:49
分子量
567.61
MOL 文件
1835667-63-4.mol
基本信息
中文別名
BEFOTERTINIB化合物BEFOTERTINIB
英文別名
CPD0557Befotertinib
lung,Epidermal growth factor receptor,D0316,D 0316,ErbB-1,Inhibitor,HER1,inhibit,cancer,EGFR,kinase,tyrosine,non-small,NSCLC
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide
2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-[1-(2,2,2-trifluoroethyl)-1H-indol-3-yl]-2-pyrimidinyl]amino]phenyl]-
物理化學(xué)性質(zhì)
密度1.26±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO : 62.5 mg/mL (110.11 mM; ultrasonic and warming and heat to 60°C)
酸度系數(shù)(pKa)12.68±0.70(Predicted)
形態(tài)Solid
顏色Light yellow to yellow