1657014-42-0
中文名稱
1657014-42-0
英文名稱
EOS-62353
CAS
1657014-42-0
分子式
C16H21BrClN5O
分子量
414.73
MOL 文件
1657014-42-0.mol
1657014-42-0 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO : 65 mg/mL (144.06 mM)
形態(tài)Solid
顏色Light yellow to yellow
應(yīng)用領(lǐng)域
用途一
GDC-0575, also known as ARRY-575 and RG7741, is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2?nM. Chk1 inhibitor GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis.常見(jiàn)問(wèn)題列表
概述
GDC-0575 dihydrochloride (ARRY-575 dihydrochloride) 是一種選擇性的，可口服的 CHK1 抑制劑，IC50 值為 1.2 nM，具有抗腫瘤活性。1657014-42-0價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | HY-112167A | 1657014-42-0 GDC-0575 dihydrochloride | 1657014-42-0 | 5mg | 1900元 |
| 2025/05/22 | HY-112167A | 1657014-42-0 GDC-0575 dihydrochloride | 1657014-42-0 | 10mM * 1mLin DMSO | 2090元 |
| 2025/05/22 | HY-112167A | 1657014-42-0 GDC-0575 dihydrochloride | 1657014-42-0 | 10mg | 3000元 |