1620278-72-9
中文名稱(chēng)
TLR7/8激動(dòng)劑1二鹽酸鹽
英文名稱(chēng)
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
CAS
1620278-72-9
分子式
C22H26ClN5
分子量
395.94
MOL 文件
1620278-72-9.mol
更新日期
2025/08/04 10:52:55
1620278-72-9 結(jié)構(gòu)式
基本信息
中文別名
二鹽酸TLR7/8 AGONIST 11-(4-(氨基甲基)芐基)-2-丁基-1H-咪唑并[4,5-C]喹啉-4-胺二鹽酸鹽
英文別名
TLR7/8 agonist-5d8 agonist 1 dihydrochloride
TLR7/8 Agonist 1 (hydrochloride)
TLR7/8 agonist 1 (dihydrochloride)
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
所屬類(lèi)別
生物化工：生化試劑物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO:83.33(Max Conc. mg/mL);192.72(Max Conc. mM)
形態(tài)固體
顏色Off-white to light yellow
InChIInChI=1S/C22H25N5.ClH/c1-2-3-8-19-26-20-21(17-6-4-5-7-18(17)25-22(20)24)27(19)14-16-11-9-15(13-23)10-12-16;/h4-7,9-12H,2-3,8,13-14,23H2,1H3,(H2,24,25);1H
InChIKeyIIFIHBPSMOIXGG-UHFFFAOYSA-N
SMILESC(C1C=CC(CN)=CC=1)N1C(=NC2C(N)=NC3=CC=CC=C3C1=2)CCCC.Cl
TLR7/8激動(dòng)劑1二鹽酸鹽價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | HY-103698A | TLR7/8激動(dòng)劑1二鹽酸鹽 TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | 1 mg | 520元 |
| 2025/05/22 | HY-103698A | 1620278-72-9 TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | 10mM * 1mLin DMSO | 1237元 |
| 2025/05/22 | HY-103698A | 1620278-72-9 TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | 5mg | 1300元 |
常見(jiàn)問(wèn)題列表
生物活性
TLR7/8 agonist 1 dihydrochloride 是一種 toll 樣受體 TLR7/TLR8 的雙重激動(dòng)劑。靶點(diǎn)
TLR7/TLR8
體外研究
TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity. TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC 50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.