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159646-83-0

中文名稱 QL9
英文名稱 QL9
CAS 159646-83-0
分子式 C52H74N10O14
分子量 1063.22
MOL 文件 159646-83-0.mol
159646-83-0 結(jié)構(gòu)式 159646-83-0 結(jié)構(gòu)式

基本信息

中文別名
TCR識別抗原多肽
英文別名
QL9
L-Leucine, L-glutaminyl-L-leucyl-L-seryl-L-prolyl-L-phenylalanyl-L-prolyl-L-phenylalanyl-L-α-aspartyl-
所屬類別
生物化工:多肽

物理化學(xué)性質(zhì)

沸點1463.5±65.0 °C(Predicted)
密度1.313±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)3.24±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
QL9價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2025/05/22HY-P0287QL9
QL9
159646-83-01mg550元
2025/05/22HY-P0287QL9
QL9
159646-83-05mg1400元
2025/05/22HY-P0287QL9
QL9
159646-83-010mg2100元

常見問題列表

生物活性
QL9 是針對2C T細(xì)胞受體 (TCR) 的高親和力同種異體抗原。
靶點

TCR

體外研究

Mouse T cell clone 2C recognizes two different major histocompatibility (MHC) ligands, the self MHC K b and the allogeneic MHC L d . Two distinct peptides, SIY (SIYRYYGL) and QL9 (QLSPFPFDL), act as strong and specific agonists when bind to K b and L d , respectively. QL9 binding to MHC L d is influenced by the majority of peptide side chains, distributed across the entire length of the peptide. Findings with both systems, but QL9-L d in particular, suggest that many single-residue substitutions, introduced into peptides to improve their binding to MHC and thus their vaccine potential, could impair T cell reactivity due to their dual impact on TCR binding. T cell activation assays are performed to measure effects of peptide SIY and QL9 residues on T cell function.

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