SFOM-0046 is an anticancer agent. It arrests the cell cycle in S-phase and causes DNA replication stress, leading to the phosphorylation of H2AX into gamma-H2AX.
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概述
SFOM-0046 可以使細(xì)胞周期停滯在 S 期，并引起 DNA 復(fù)制應(yīng)激，導(dǎo)致 H2AX 磷酸化為 γ-H2AX。SFOM-0046 會(huì)誘導(dǎo) DNA 損傷。SFOM-0046 是一種有效的抗癌劑。
