1287585-40-3

基本信息
N-acetyl lysyltyrosylcysteine amide(Myeloperoxidase inhibitor KYC)
物理化學(xué)性質(zhì)
報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
2025/05/22 | HY-125039 | N-ACETYL LYSYLTYROSYLCYSTEINE AMIDE N-Acetyl lysyltyrosylcysteine amide | 1287585-40-3 | 1 mg | 900元 |
2025/05/22 | HY-125039 | N-ACETYL LYSYLTYROSYLCYSTEINE AMIDE N-Acetyl lysyltyrosylcysteine amide | 1287585-40-3 | 5 mg | 2250元 |
2025/05/22 | HY-125039 | N-ACETYL LYSYLTYROSYLCYSTEINE AMIDE N-Acetyl lysyltyrosylcysteine amide | 1287585-40-3 | 10 mM * 1 mLin Water | 2500元 |
常見問題列表
N-Acetyl lysyltyrosylcysteine amide (KYC) significantly decreases infarct size, blood-brain barrier leakage, infiltration of myeloid cells, loss of neurons, and apoptosis in the brains of middle cerebral artery occlusion (MCAO) mice.
N-Acetyl lysyltyrosylcysteine amide (10 mg/kg; i.p.; daily for 3-7 days) significantly reduces neurological severity scores and infarct size in MCAO mice.
N-Acetyl lysyltyrosylcysteine amide (10 mg/kg; i.p.; daily 7 days) significantly protects BBB function and decreased neutrophil infiltration. N-Acetyl lysyltyrosylcysteine amide (10 mg/kg; i.p.; daily 7 days) significantly reduces microglia/macrophage activation and neuron loss in MCAO mice. N-Acetyl lysyltyrosylcysteine amide (10 mg/kg; i.p.; daily for 3-7 days) decreases apoptosis and cell injury in the brains of MCAO mice. N-Acetyl lysyltyrosylcysteine amide reduced MPO in the brains of MCAO mice. N-Acetyl lysyltyrosylcysteine amide reduces NO2Tyr and 4-HNE in MCAO mice.
Animal Model: | 8-10 weeks old C57BL/6J mice (middle cerebral artery occlusion (MCAO) mode) |
Dosage: | 10 mg/kg |
Administration: | I.p.; daily for 3-7 days |
Result: | Significantly reduced neurological deficit and brain infarct size in mice subjected to MCAO. |