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124070-15-1

中文名稱 5-aminocarbonyl-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5,10-imine
英文名稱 5-aminocarbonyl-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5,10-imine
CAS 124070-15-1
MOL 文件 124070-15-1.mol
124070-15-1 結(jié)構(gòu)式 124070-15-1 結(jié)構(gòu)式

基本信息

中文別名
化合物 T26564
英文別名
SGB017
SGB-017
SGB 017
5-aminocarbonyl-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5,10-imine

應(yīng)用領(lǐng)域

用途一
ADCI, also known as SGB-017, is a glutamate receptor antagonist potentially for the treatment of epilepsy. ADCI blocks both voltage-activated sodium channels and N-methyl-D-aspartate (NMDA)-receptor-gated channels. Inhibition of sodium channels by ADCI was voltage dependent. High doses of ADCI increased dopamine metabolism in the prefrontal cortex and/or in the nucleus accumbens, but not in the dorsal striatum.

常見問題列表

概述
ADCI 是一種非競爭性 NMDA 拮抗劑,是一種廣譜抗驚厥劑。
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