| Identification | Back Directory | [Name]
ACA | [CAS]
99196-74-4 | [Synonyms]
ACA
ACL
AMARANTHUS CAUDATUS LECTIN
GAMRBCZMOOMBSQ-CCEZHUSRSA-N
N-(4-Pentylcinnamoyl)anthranilic acid
N-(p-Amylcinnamoyl)anthranilic acid >=98% (HPLC)
2-[3-(4-pentylphenyl)prop-2-enoylamino]benzoic acid
2-[[1-oxo-3-(4-Pentylphenyl)-2-propen-1-yl]amino]-benzoic acid | [Molecular Formula]
C21H23NO3 | [MDL Number]
MFCD01321668 | [MOL File]
99196-74-4.mol | [Molecular Weight]
337.41 |
| Chemical Properties | Back Directory | [Boiling point ]
563.1±50.0 °C(Predicted) | [density ]
1.178±0.06 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
DMSO: ≥20mg/mL | [form ]
powder | [pka]
3.46±0.36(Predicted) | [color ]
white to off-white |
| Hazard Information | Back Directory | [Uses]
N-(p-Amylcinnamoyl)anthranilic acid has been used as a transient receptor potential cation channel subfamily M member 2 (TRPM2) inhibitor, in studying its role in regulating the production of reactive oxygen species (ROS). | [Definition]
ChEBI: N-(p-amylcinnamoyl)anthranilic acid is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 4-pentylcinnamoyl group. It is a transient receptor potential (TRP) channel blocker and phospholipase A2 (PLA2) inhibitor. It has a role as an EC 3.1.1.4 (phospholipase A2) inhibitor and a TRP channel blocker. It is an amidobenzoic acid, a member of cinnamamides and a secondary carboxamide. | [General Description]
N-(p-Amylcinnamoyl)anthranilic acid (ACA) functions as a broad spectrum phospholipase A2 inhibitor and blocks transient receptor potential (TRP) channels. It inhibits calcium activated chloride current in cardiac ventricular myocytes. ACA regulates various ion channels. | [Biochem/physiol Actions]
Broad spectrum phospholipase A2 (PLA2) inhibitor and TRP channel blocker. |
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