| Identification | Back Directory | [Name]
GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA | [CAS]
99026-77-4 | [Synonyms]
[ALA107]-MBP (104-118)
[ALA107]-MBP FRAGMENT 104-118
[Ala107]-Myelin Basic Protein (104-118)
[ALA107]-MYELIN BASIC PROTEIN FRAGMENT 104-118
GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA
L-Alanine, glycyl-L-lysylglycyl-L-alanylglycyl-L-leucyl-L-seryl-L-leucyl-L-seryl-L-arginyl-L-phenylalanyl-L-seryl-L-tryptophylglycyl- (9CI)
(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-6-amino-2-[(2-aminoacetyl)amino]hexanoyl]amino]acetyl]amino]propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]acetyl]amino]propanoic acid | [Molecular Formula]
C67H104N20O19 | [MDL Number]
MFCD00273540 | [MOL File]
99026-77-4.mol | [Molecular Weight]
1493.67 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [solubility ]
Soluble to 1 mg/ml in 10% acetonitrile | [form ]
solid | [color ]
White | [biological source]
human | [Sequence]
H-Gly-Lys-Gly-Ala-Gly-Leu-Ser-Leu-Ser-Arg-Phe-Ser-Trp-Gly-Ala-OH |
| Hazard Information | Back Directory | [Biological Activity]
[ala107]-mbp (104-118) is a non-competitive inhibitor of pkc and synthetic peptide analog of bovine myelin basic protein (mbp) with ic50 value of 46 - 145 mm.1. substrate specificity of phospholipid/ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein. turner et al. j.biol.chem., 1985;260:115032. synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase c). su et al. biochem.biophys.res.commun., 1986;134:78 | [Biochem/physiol Actions]
[Ala107]-Myelin Basic Protein Fragment 104-118 is an inhibitor of protein kinase C. | [storage]
Desiccate at -20°C |
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