| Identification | Back Directory | [Name]
BENZYL 6-OXOHEXYLCARBAMATE | [CAS]
98648-05-6 | [Synonyms]
BENZYL 6-OXOHEXYLCARBAMATE
Benzyl 6-Oxohexylcarbamate
DISCONTINUED | [Molecular Formula]
C14H19NO3 | [MDL Number]
MFCD12031811 | [MOL File]
98648-05-6.mol | [Molecular Weight]
249.31 |
| Hazard Information | Back Directory | [Description]
Benzyl (6-oxohexyl)carbamate is a PEG linker containing an aldehyde group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The aldehyde can be used in PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine. | [Uses]
Benzyl (6-oxohexyl)carbamate is a linker containing an aldehyde group and a benzyl (Cbz) protecting group. The aldehyde can react with hydrazine or hydrazide to form a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine. |
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