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ChemicalBook--->CAS DataBase List--->958323-31-4

958323-31-4

958323-31-4 Structure

958323-31-4 Structure
IdentificationBack Directory
[Name]

TLX agonist 1
[CAS]

958323-31-4
[Synonyms]

TLX agonist 1
Methanone, (1,5-dimethyl-1H-pyrazol-3-yl)[4-(diphenylmethyl)-1-piperazinyl]-
[Molecular Formula]

C23H26N4O
[MOL File]

958323-31-4.mol
[Molecular Weight]

374.48
Chemical PropertiesBack Directory
[Boiling point ]

539.6±50.0 °C(Predicted)
[density ]

1.16±0.1 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

DMSO: 62.5 mg/mL (166.90 mM)
[form ]

Solid
[pka]

5.78±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

TLX agonist 1 (ccrp2) is an orphan nuclear receptor tailless (TLX, NR2E1) modulator (EC50=1μM; Kd= 650 nM). TLX agonist 1 potentiates TLX transcriptional repressive activity[1].
[storage]

Store at -20°C
[References]

[1] Benod C, et al. The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable. PLoS One. 2014 Jun 17;9(6):e99440. DOI:10.1371/journal.pone.0099440
Spectrum DetailBack Directory
[Spectrum Detail]

TLX agonist 1(958323-31-4)1HNMR
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