| Identification | Back Directory | [Name]
SGI-110 | [Synonyms]
SGI-110
CS-1302
Guadecitabine
SGI110;SGI 110
SGI-110 ammonium salt
SGI-110 Guadecitabine
2'-Deoxy-5-azacytidylyl-(3'-5')-2'-deoxyguanosine
Guanosine, 2'-deoxy-5-azacytidylyl-(3'→5')-2'-deoxy- | [MDL Number]
MFCD28144509 | [MOL File]
929901-49-5.mol |
| Chemical Properties | Back Directory | [Boiling point ]
956.4±75.0 °C(Predicted) | [density ]
2.24±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C,unstable in solution, ready to use. | [solubility ]
H2O | [form ]
Powder | [pka]
1.37±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [in vivo]
Guadecitabine (S110) is effective at retarding tumor growth. While the tumors do not shrink in size with Guadecitabine treatment, they experience very minimal growth while the tumors treated with PBS only show substantial growth. In addition, Guadecitabine induces much less toxicity as determined by mouse weight changes when given subcutaneously (SQ) compare to that with IP injections[3]. | [target]
DNA Methyltransferase | [IC 50]
DNA Methyltransferase |
|
| Company Name: |
NCE Biomedical Co.,Ltd.
|
| Tel: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
m.approvedhomemanagement.com/ShowSupplierProductsList15748/0.htm |
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Cckinase, Inc.
|
| Tel: |
+1 (732)236-3202 |
| Website: |
www.cckinase.com |
|