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ChemicalBook--->CAS DataBase List--->926906-64-1

926906-64-1

926906-64-1 Structure

926906-64-1 Structure
IdentificationBack Directory
[Name]

VRX-0466617
[CAS]

926906-64-1
[Synonyms]

VRX-0466617
[Molecular Formula]

C19H20BrN5O2S
[MDL Number]

MFCD30146479
[MOL File]

926906-64-1.mol
[Molecular Weight]

462.36
Chemical PropertiesBack Directory
[density ]

1.59±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

6.75±0.60(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

VRX-0466617 is a novel selective inhibitor for Chk2.
[Uses]

VRX0466617, a selective Chk2 inhibitor, inhibits the phosphorylation of Chk2 Ser 19 and Ser33-35. VRX0466617 can be used in the study of cancer[1].
[References]

[1] Carlessi L, et al. Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2. Mol Cancer Ther. 2007 Mar;6(3):935-44. DOI:10.1158/1535-7163.MCT-06-0567
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