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ChemicalBook--->CAS DataBase List--->91742-10-8

91742-10-8

91742-10-8 Structure

91742-10-8 Structure
IdentificationBack Directory
[Name]

HA-1004 HYDROCHLORIDE WEAK PROTEIN KINAS E I
[CAS]

91742-10-8
[Synonyms]

ht1004
H-1004
HA 1004,HA1004
HA-1004 HYDROCHLORIDE WEAK PROTEIN KINAS E I
n-(2-((aminoiminomethyl)amino)ethyl)-5-isoquinolinesulfonamid
n-(2-((aminoiminomethyl)amino)ethyl)-5-isoquinolinesulfonamide
5-Isoquinolinesulfonamide, N-(2-((aminoiminomethyl)amino)ethyl)-
[Molecular Formula]

C12H15N5O2S
[MOL File]

91742-10-8.mol
[Molecular Weight]

293.345
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.
[Definition]

ChEBI: 2-[2-(5-isoquinolinylsulfonylamino)ethyl]guanidine is a member of isoquinolines.
[in vivo]

HA-1004 (40 nmol/day; infused by minipumps and delivered at 1 μL/h), it acts simultaneously with morphine to antagonize the phosphorylation of ERK1/2 and TH and inhibit the increase of NA conversion during morphine withdrawal in rats[1].

Spectrum DetailBack Directory
[Spectrum Detail]

HA-1004 HYDROCHLORIDE WEAK PROTEIN KINAS E I(91742-10-8)1HNMR
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