| Identification | Back Directory | [Name]
3H-Oxireno[7,8]naphtho[8a,1-b]furan-3-one, decahydro-4,7,9a-trimethyl-, (1aR,1bR,4R,4aS,7R,7aS,9aR)- (9CI) | [CAS]
87206-33-5 | [Synonyms]
(3R)-dihydroarteannuin B
inhibit,Dihydroarteannuin B,Inhibitor
3H-Oxireno[7,8]naphtho[8a,1-b]furan-3-one, decahydro-4,7,9a-trimethyl-, (1aR,1bR,4R,4aS,7R,7aS,9aR)- (9CI) | [Molecular Formula]
C15H22O3 | [MDL Number]
MFCD34471642 | [MOL File]
87206-33-5.mol | [Molecular Weight]
250.33 |
| Chemical Properties | Back Directory | [Boiling point ]
387.1±25.0 °C(Predicted) | [density ]
1.16±0.1 g/cm3(Predicted) | [InChI]
InChI=1S/C15H22O3/c1-8-4-5-11-9(2)12(16)17-15(11)10(8)6-7-14(3)13(15)18-14/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1 | [InChIKey]
VWGPQZZLIAQJCE-NNWCWBAJSA-N | [SMILES]
O1C(=O)[C@H](C)[C@]2([H])CC[C@@H](C)[C@@]3([H])[C@@]12[C@]1([H])O[C@]1(C)CC3 |
| Hazard Information | Back Directory | [Uses]
Dihydroarteannuin B, a natural Dihydroarteannuin, is an microbial metabolite of Arteannuin B[1]. | [References]
[1] Wei-dong Li, et al. Dihydroarteannuin ameliorates lupus symptom of BXSB mice by inhibiting production of TNF-alpha and blocking the signaling pathway NF-kappa B translocation. Int Immunopharmacol. 2006 Aug;6(8):1243-50. DOI:10.1016/j.intimp.2006.03.004
[2] Lai-King Sy, et al. A novel endoperoxide and related sesquiterpenes from Artemisia annua which are possibly derived from allylic hydroperoxides. Tetrahedron Volume 54, Issue 17, 23 April 1998, Pages 4345-4356. |
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