Identification | Back Directory | [Name]
N-(2,4-dimethylphenyl)sulfonyl-2-naphthalen-2-yloxyacetamide | [CAS]
868145-09-9 | [Synonyms]
I942 I-942 I 942 N-(2,4-dimethylphenyl)sulfonyl-2-naphthalen-2-yloxyacetamide | [Molecular Formula]
C20H19NO4S | [MOL File]
868145-09-9.mol | [Molecular Weight]
369.43 |
Hazard Information | Back Directory | [Description]
I942 EPAC1 agonist, also known as I942, is a first in class, isoform selective non-cyclic nucleotide (NCN) EPAC1 agonist. | [Uses]
I942 is a first in class, selective non-cyclic nucleotide (NCN) EPAC1 agonist. I942 can attenuate proinflammatory cytokine signalling normally associated with cardiovascular diseases[1]. | [References]
[1] Graeme Barker, et al. The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation. J Cardiovasc Dev Dis. 2017 Dec 5;4(4):22. DOI:10.3390/jcdd4040022 |
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