| Identification | Back Directory | [Name]
Acetic acid, 2-[3-[[(3',4-difluoro[1,1'-biphenyl]-3-yl)carbonyl]amino]phenoxy]- | [CAS]
863704-91-0 | [Synonyms]
PGN9856
Acetic acid, 2-[3-[[(3',4-difluoro[1,1'-biphenyl]-3-yl)carbonyl]amino]phenoxy]- | [Molecular Formula]
C21H15F2NO4 | [MOL File]
863704-91-0.mol | [Molecular Weight]
383.34 |
| Chemical Properties | Back Directory | [Boiling point ]
510.3±50.0 °C(Predicted) | [density ]
1.383±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.10±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
PGN-9856 is a selective and high affinity (pKi ≥ 8.3) ligand at EP2 receptor. PGN-9856 is a potetn and non-prostanoid EP2 receptor agonist (pEC50 ≥ 8.5). PGN-9856 shows anti-inflammatory and anti-glaucoma activities[1]. | [IC 50]
EP2: ≥ 8.5 (pEC50); EP2: ≥ 8.3 (pKi) | [References]
[1] Coleman RA, et al. The affinity, intrinsic activity and selectivity of a structurally novel EP2 receptor agonist at human prostanoid receptors. Br J Pharmacol. 2019 Mar;176(5):687-698. DOI:10.1111/bph.14525 |
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-8447131 13564518121 |
| Website: |
m.approvedhomemanagement.com/showsupplierproductslist927327/0.htm |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
|