| Identification | Back Directory | [Name]
CAY10576 | [CAS]
862812-98-4 | [Synonyms]
CAY10576
IKK-3 Inhibitor
5-(5,6-dimethoxybenzimidazol-1-yl)-3-[(2-methylsulfonylphenyl)methoxy]thiophene-2-carbonitrile
5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile
2-Thiophenecarbonitrile, 5-(5,6-diMethoxy-1H-benziMidazol-1-yl)-3-[[2-(Methylsulfonyl)phenyl]Methoxy]- | [Molecular Formula]
C22H19N3O5S2 | [MDL Number]
MFCD10567700 | [MOL File]
862812-98-4.mol | [Molecular Weight]
469.53 |
| Chemical Properties | Back Directory | [Boiling point ]
744.4±70.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 45 mg/mL (95.84 mM; Need ultrasonic) | [form ]
Powder | [pka]
3.09±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
GSK 319347A is a potent and selective IKKε kinase inhibitor. | [Definition]
ChEBI: 5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(2-methylsulfonylphenyl)methoxy]-2-thiophenecarbonitrile is a member of benzimidazoles. | [Biological Activity]
Cell permeable: no''Primary Target
IKK-3''Product competes with ATP.''Reversible: no''Target IC50: 40 nM against IKK-3 (IKK-ε) | [IC 50]
TBK1: 93 nM (IC50); IKK-ε: 469 nM (IC50); IKK2: 790 nM (IC50) | [storage]
Store at -20°C |
|
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
| Company Name: |
amyjetsci
|
| Tel: |
027-59626688 18771149750 |
| Website: |
https://www.amyjet.com/ |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|