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ChemicalBook--->CAS DataBase List--->862811-76-5

862811-76-5

862811-76-5 Structure

862811-76-5 Structure
IdentificationBack Directory
[Name]

Benzamide, 3,4-difluoro-N-[3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl]-
[CAS]

862811-76-5
[Synonyms]

NCGC00135472
Benzamide, 3,4-difluoro-N-[3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl]-
[Molecular Formula]

C20H14F2N4O
[MOL File]

862811-76-5.mol
[Molecular Weight]

364.35
Chemical PropertiesBack Directory
[storage temp. ]

room temp
[solubility ]

DMSO: 2mg/mL, clear
[form ]

powder
[color ]

white to beige
Hazard InformationBack Directory
[Description]

NCGC00135472 is an gonist for human Resolvin D1 Receptor DRV1 with pro-resolving functions.
[Uses]

NCGC00135472 is a potent agonist of resolvin D1 receptor (DRV1), with the EC50 of 0.37 nM and 0.05 μM for β-arrestin and cAMP activities, respectively[1].
[References]

[1] Nan Chiang, et al. Identification of Chemotype Agonists for Human Resolvin D1 Receptor DRV1 with Pro-Resolving Functions. Cell Chem Biol. 2019 Feb 21;26(2):244-254.e4. DOI:10.1016/j.chembiol.2018.10.023
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