| Identification | Back Directory | [Name]
N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide | [CAS]
839707-37-8 | [Synonyms]
CS-2337
CS-2160
Pluripotin
SC1 (Pluripotin)
Pluripotin (SC-1)
N-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimid
N-[3-[7-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-1-methyl-2-oxo-1,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-3-yl]-4-methylphenyl]-3-trifluoromethyl-benzamide
N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
N-[3-[7-[(1,3-Dimethyl-1H-pyrazol-5-yl)amino]-1,4-dihydro-1-methyl-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide | [EINECS(EC#)]
804-647-7 | [Molecular Formula]
C27H25F3N8O2 | [MDL Number]
MFCD20527253 | [MOL File]
839707-37-8.mol | [Molecular Weight]
550.53 |
| Chemical Properties | Back Directory | [density ]
1.43 | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble10mg/mL (clear solution) | [form ]
powder | [pka]
12.82±0.70(Predicted) | [color ]
white to beige | [InChIKey]
NBZFRTJWEIHFPF-UHFFFAOYSA-N |
| Hazard Information | Back Directory | [Uses]
Pluripotin is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Pluripotin has been shown to maintain embryonic stem cell (ESC) self-renewal. When combined with leukemia inhibitory factor, Pluripotin greatly promotes derivation of embryonic stem cell lines from refractory strains. | [Biological Activity]
Pluripotin is an activator of murine embryonic stem (ES) cell self-renewal. It appears th at pluripotin mediates the activity by dual RasGAP and ERK1 inhibition. | [storage]
Store at -20°C |
|
| Company Name: |
NCE Biomedical Co.,Ltd.
|
| Tel: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
m.approvedhomemanagement.com/ShowSupplierProductsList15748/0.htm |
|