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ChemicalBook--->CAS DataBase List--->810668-53-2

810668-53-2

810668-53-2 Structure

810668-53-2 Structure
IdentificationBack Directory
[Name]

MQCKXANXFRGFND-CGIARSFXSA-N
[CAS]

810668-53-2
[Synonyms]

Resolvin D2 methyl ester
MQCKXANXFRGFND-CGIARSFXSA-N
4,8,10,12,14,19-Docosahexaenoic acid, 7,16,17-trihydroxy-, methyl ester, (4Z,7S,8E,10Z,12E,14E,16R,17S,19Z)-
[Molecular Formula]

C23 H34 O5
[MOL File]

810668-53-2.mol
[Molecular Weight]

390.51
Chemical PropertiesBack Directory
[Boiling point ]

562.1±50.0 °C(Predicted)
[density ]

1.064±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml
[pka]

13.38±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
Hazard InformationBack Directory
[Description]

Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation. RvD2 methyl ester is a methyl ester version of the free acid which may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
[Uses]

Resolvin D2 Methyl Ester acts as a lipophilic prodrug form while in the free acid state which alters its distribution and pharmacokinetic properties.
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