| Identification | Back Directory | [Name]
HL 725 | [CAS]
78416-81-6 | [Synonyms]
HL 725
HL 725 HCL
TREQUINSIN
Trequinsin, HCl
TREQUINSIN HYDROCHLORIDE
DTCZZBVPTHVXFA-OSMRDGEFSA-N
TREQUINSIN HYDROCHLORIDE MINIMUM 98%
4,6-trimethylphenyl)imino)--2-((monohydrochloride
Trequinsin, Hydrochloride - CAS 78416-81-6 - Calbiochem
4h-pyrimido(6,1-a)isoquinolin-4-one,2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl
9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-(6,1-A)-ISOQUINOLIN-4-ONE, HCL
9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-[6,1A]-ISOQUINOLIN-4-ONE HYDROCHLORIDE
2,3,6,7-Tetrahydro-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-4H-pyrimido[6,1-a]isoquinolin-4-onehydrochloride
2,3,6,7-TETRAHYDRO-9,10-DIMETHOXY-3-METHYL-2-[(2,4,6-TRIMETHYLPHENYL)IMINO]-4H-PYRIMIDO[6,1-A]ISOQUINOLIN-4-ONE HYDROCHLORIDE
4H-Pyrimido(6,1-A)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride | [Molecular Formula]
C24H28ClN3O3 | [MDL Number]
MFCD01076563 | [MOL File]
78416-81-6.mol | [Molecular Weight]
441.95 |
| Chemical Properties | Back Directory | [Melting point ]
210-211 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7)) | [storage temp. ]
Desiccate at RT | [solubility ]
DMSO: 100 mM; Ethanol: 100 mM | [form ]
Pale yellow solid | [color ]
Light yellow to yellow | [Water Solubility ]
water: 500μM |
| Hazard Information | Back Directory | [Uses]
PDE inhibitor | [Biological Activity]
Extremely potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3; IC 50 = 250 pM). Potently inhibits arachidonic acid-induced aggregation of human platelets (IC 50 = 50 pM). Orally active antihypertensive agent; reduces systemic blood pressure in both normotensive and hypertensive animal models. | [storage]
Desiccate at RT |
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821-50328103-801 18930552037 |
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Energy Chemical
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021-58432009 400-005-6266 |
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guoyungurui
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18162595016; 18162595016 |
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R&D Systems, Inc
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18003437475 18003437475 |
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www.rndsystems.com |
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Merck Millipore
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1-400-889-1988 400-889-1988 |
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www.merckmillipore.com |
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