| Identification | Back Directory | [Name]
Tris(3-hydroxypropyltriazolylMethyl)aMine 95% | [CAS]
760952-88-3 | [Synonyms]
THPTA
Tris(3-hydroxypropyltriazolylMethyl)a
tris(3-hydroxypropyltriazolymethyl)amine
Tris(3-hydroxypropyltriazolylmethyl)amine
Tris(3-hydroxypropyltriazolylMethyl)aMine95%
Tris(3-hydroxypropyltriazolylMethyl)aMine 95%
4,4',4''-Nitrilotris(4-(1H-1,2,3-triazol-4-yl)butan-1-ol)
Tris[[1-(3-hydroxypropyl)-1H-1,2,3-triazol-4-yl]methyl]amine
1H-1,2,3-Triazole-1-propanol, 4,4',4''-[nitrilotris(methylene)]tris-
3,3′,3′′-(4,4′,4′′-(Nitrilotris(methylene))tris(1H-1,2,3-triazole-4,1-diyl))tris(propan-1-ol)
3,3',3''-((4,4'4,”-nitrilotris(methylene))tris(1H-1,2,3-triazole-5,1-diyl))tris(propan-1-ol) -(THPTA) | [Molecular Formula]
C18H30N10O3 | [MDL Number]
MFCD27665386 | [MOL File]
760952-88-3.mol | [Molecular Weight]
434.496 |
| Chemical Properties | Back Directory | [Melting point ]
331-336°C (decomposition) | [Boiling point ]
723.8±70.0 °C(Predicted) | [density ]
1.44±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Methanol (Very Slightly) | [form ]
Solid | [pka]
14.34±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
THPTA is a water-soluble, very effective ligand for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). It serves a dual purpose: 1) Acceleration of the CuAAC reaction by maintaining the Cu(I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction.
THPTA is a superior alternative to water-insoluble TBTA.
a) J. Am. Chem. Soc. 2011, 133, 17993.
b) Bioconjugate Chem. 2010, 21, 1912. | [Uses]
Tris(3-hydroxypropyltriazolylmethyl)amine when complexed to copper(I) can be used as a catalyst. | [reaction suitability]
reaction type: click chemistry | [storage]
Store at -20°C |
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| Company Name: |
Energy Chemical
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| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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