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ChemicalBook--->CAS DataBase List--->757251-39-1

757251-39-1

757251-39-1 Structure

757251-39-1 Structure
IdentificationBack Directory
[Name]

4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
[CAS]

757251-39-1
[Synonyms]

Regofenib impurity 4
Regorafenib USP RC A
Regorafenib Impurity 35
Regorafenib Intermediate
Regorafenib EP Impurity A
4-(4-amino-3-fluorophenoxy)
AFP-Picolin Methylamide Impurity
4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLIMIDE
4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLINAMIDE
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide EINECS
4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamid
4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYL-2-PYRIDINECARBOXAMIDE
2-Pyridinecarboxamide,4-(4-amino-3-fluorophenoxy)-N-methyl-
4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamine
4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide
AFP-Picolin Methylamide ImpurityQ: What is AFP-Picolin Methylamide Impurity Q: What is the CAS Number of AFP-Picolin Methylamide Impurity Q: What is the storage condition of AFP-Picolin Methylamide Impurity Q: What are the applications of AFP-Picolin Methylamide Impurity
[EINECS(EC#)]

692-721-8
[Molecular Formula]

C13H12FN3O2
[MDL Number]

MFCD09033852
[MOL File]

757251-39-1.mol
[Molecular Weight]

261.25
Chemical PropertiesBack Directory
[Melting point ]

143 °C
[Boiling point ]

459.8±45.0 °C(Predicted)
[density ]

1.305
[vapor pressure ]

0Pa at 20℃
[storage temp. ]

Keep in dark place,Sealed in dry,Room Temperature
[solubility ]

Chloroform (Slightly), DMSO (Sparingly), Methanol (Slightly)
[form ]

Solid
[pka]

13.92±0.46(Predicted)
[color ]

Orange to Dark Red to Brown
[Water Solubility ]

190mg/L at 20℃
[LogP]

1.3 at 25℃
Safety DataBack Directory
[HS Code ]

2933.39.9200
Hazard InformationBack Directory
[Chemical Properties]

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide has the appearance of a white to yellow powder or crystals, which is stable and non-reactive under normal conditions of use, storage and transport.
[Uses]

4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer.
[Definition]

ChEBI: 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide is an aromatic ether.
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