| Identification | Back Directory | [Name]
N,N,1-trimethylpyridin-4-amine iodide | [CAS]
7538-79-6 | [Synonyms]
N,N,1-trimethylpyridin-4-amine iodide
4-(Dimethylamino)-1-methylpyridinium iodide | [Molecular Formula]
C8H13IN2 | [MOL File]
7538-79-6.mol | [Molecular Weight]
264.107 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
4-(Dimethylamino)-1-methylpyridinium is a monoquaternary pyridinium salt with anticholinesterase and antiproliferative activities.1,2 It inhibits cholinesterase activity in rat brain homogenates with a Kd value of 33 μM and yeast choline kinase (ChoK) with an IC50 value of 17 μM. 4-(Dimethylamino)-1-methylpyridinium also has antiproliferative activity against HT-29 colon cancer cells (IC50 = 2 μM).2 | [Uses]
4-(Dimethylamino)-1-methylpyridinium iodide is a biochemical reagent. | [storage]
Store at -20°C | [References]
1. Jun, D., Paar, M., Binder, J., et al. Preparation and in vitro evaluation of monoquaternary inhibitors of brain cholinesterases Lett. Org. Chem. 6(6),500-503(2009).
2. Campos, J., del Carmen Nú?ez, M., Rodríguez, V., et al. LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase Eur. J. Med. Chem. 36(3),215-225(2001). |
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| Company Name: |
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16314854226 |
| Website: |
www.bocsci.com |
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