| Identification | Back Directory | [Name]
(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE | [CAS]
745055-86-1 | [Synonyms]
UBP 296
(RS)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE | [Molecular Formula]
C15H15N3O6 | [MDL Number]
MFCD06411606 | [MOL File]
745055-86-1.mol | [Molecular Weight]
333.3 |
| Hazard Information | Back Directory | [Uses]
UBP 296 is a novel, potent and selective kainate receptor antagonist. | [Definition]
ChEBI: 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxo-1-pyrimidinyl]methyl]benzoic acid is an alpha-amino acid. | [Biological Activity]
Selective and potent GluR5-subunit containing kainate receptor antagonist (apparent K D = 1.09 mM). Displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. Has little or no action at NMDA or group I mGlu receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres. | [storage]
Store at RT |
|
| Company Name: |
|
| Tel: |
821-50328103-801 18930552037 |
| Website: |
http://m.approvedhomemanagement.com/ShowSupplierProductsList13285/0.htm |
| Company Name: |
R&D Systems, Inc
|
| Tel: |
18003437475 18003437475 |
| Website: |
www.rndsystems.com |
|