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ChemicalBook--->CAS DataBase List--->73912-52-4

73912-52-4

73912-52-4 Structure

73912-52-4 Structure
IdentificationBack Directory
[Name]

5-Methacrylamidoisophthalic acid
[CAS]

73912-52-4
[Synonyms]

MS 15203
CHEMBRDG-BB 5186719
MS0015203 >=98% (HPLC)
5-Methacrylamidoisophthalic acid
5-(METHACRYLOYLAMINO)ISOPHTHALIC ACID
5-(methacryloylamino)isophthalic acid(SALTDATA: FREE)
5-[(2-Methyl-1-oxo-2-propen-1-yl)amino]-1,3-benzenedicarboxylic acid
[Molecular Formula]

C12H11NO5
[MDL Number]

MFCD00434754
[MOL File]

73912-52-4.mol
[Molecular Weight]

249.22
Chemical PropertiesBack Directory
[Melting point ]

297 °C(Solv: ethanol (64-17-5); water (7732-18-5))
[Boiling point ]

561.3±50.0 °C(Predicted)
[density ]

1.420±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

3.36±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H319
[Precautionary statements ]

P301+P312+P330-P305+P351+P338
Hazard InformationBack Directory
[Uses]

MS 15203. is a potent and selective agonist of the neuropeptide receptor GPR171. It has also been shown to increases neuronal activity in the paraventricular nucleus, and to ncrease food intake and body weight in mice.
[Biological Activity]

MS0015203 is a potent and selective agonist of the neuropeptide receptor GPR171. MS0015203 increases food intake and body weight in mice.
[in vivo]

MS15203 (MS0015203) (3 mg/kg; i.p.) causes an increase in neuronal activity within cells containing GPR171 in the PVN[1].
. MS15203 (3 mg/kg; i.p.) significantly increases food intake at 4 and 8 hours[1].
MS15203 (3 mg/kg; i.p.) significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1].

[storage]

Store at -20°C
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