| Identification | Back Directory | [Name]
(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride | [CAS]
72795-01-8 | [Synonyms]
CS-769
CI 118551 Hydrochloride
ICI 118,551 hydrochloride, >=98%
(2R,3R)-rel-1-[(2,3-Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride (1:1)
(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride | [Molecular Formula]
C17H28ClNO2 | [MOL File]
72795-01-8.mol | [Molecular Weight]
313.863 |
| Chemical Properties | Back Directory | [storage temp. ]
desiccated | [solubility ]
DMSO : 25 mg/mL (79.65 mM; Need ultrasonic)H2O : 12.5 mg/mL (39.83 mM; Need ultrasonic) | [form ]
powder | [color ]
white | [Water Solubility ]
H2O: >10mg/mL |
| Hazard Information | Back Directory | [Description]
ICI 118551 is a potent, selective antagonist of the β2-adrenergic receptor (Ki = 0.7 nM for the β2receptor, compared with 49.5 and 611 nM for β1 and β3 receptors, respectively). It is active in vivo and is often used to evaluate the actions of adrenergic receptor agonists. | [Uses]
The (R,R)-enantiomer | [Biochem/physiol Actions]
ICI 118,551 has been used to treat vasomotor migraines and somatic troubles related to anxiety state. | [storage]
Store at -20°C |
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