| Identification | Back Directory | [Name]
(5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOSATETRAENOIC ACID | [CAS]
71548-19-1 | [Synonyms]
5(S), 12(S)-DIHETE
6-TRANS-12-EPI-LTB4
6E-12-EPI-LEUKOTRIENE B4
6-TRANS-12-EPI LEUKOTRIENE B4
Delta(6)-trans-12-epi-leukotriene B4
6-trans-12-epi Leukotriene B4 Lipid Maps MS Standard
(5S,12S)-DIHYDROXY-(6E,8E,10E,14Z)-EICOSATETRAENOIC ACID
5(S),12(S)-DIHYDROXYEICOSA-6E,8E,10E,14Z-TETRAENOIC ACID
(5S,6E,8E,10E,12S,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid | [Molecular Formula]
C20H32O4 | [MDL Number]
MFCD00065851 | [MOL File]
71548-19-1.mol | [Molecular Weight]
336.47 |
| Chemical Properties | Back Directory | [Boiling point ]
536.4±50.0 °C(Predicted) | [density ]
1.040±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml | [pka]
4.66±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
6-trans-12-epi Leukotirene B4 (LTB4) is a non-enzymatic hydrolysis product of LTA4. It was originally isolated from glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNL). 6-trans-12-epi LTB4 is weakly chemotactic for PMNL, with approximately 20 times less potency than LTB4, and has no effect on the aggregation response. | [Uses]
6-trans-12-epi Leukotriene B4 is a product of the non-enzymatic hydrolysis of LTA4. | [Definition]
ChEBI: A leukotriene that is the 6-trans,12S-isomer of leukotriene B4. | [IC 50]
Human Endogenous Metabolite |
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