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ChemicalBook--->CAS DataBase List--->71308-34-4

71308-34-4

71308-34-4 Structure

71308-34-4 Structure
IdentificationBack Directory
[Name]

AG 1406
[CAS]

71308-34-4
[Synonyms]

AG 1406
AG1406;AG-1406
2-[[4-HYDROXY-3,5-DI(PROPAN-2-YL)PHENYL]METHYLIDENE]PROPANEDINITRILE
Propanedinitrile, 2-[[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-
[Molecular Formula]

C16H18N2O
[MDL Number]

MFCD31620835
[MOL File]

71308-34-4.mol
[Molecular Weight]

254.33
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

AG 1406 (compound M19) is a HER2 inhibitor, with an IC50 of 10.57 μM for HER2 in BT474 cell and >50 μM for EGFR in EGF-3T3 cell[1].
[References]

[1] Hui Chen, et al. Methods and compositions for inhibiting cell proliferative disorders. Patent, US5789427A.
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