| Identification | Back Directory | [Name]
2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE | [CAS]
71119-11-4 | [Synonyms]
Bucindolol
Bucindololum
Unii-E9uo06K7ce
Bucindololum [inn-latin]
3-[2-[3-(o-Cyanophenoxy)-2-hydroxypropylamino]-2-methylpropyl]-1H-indole
2-[2-HYDROXY-3-[2-(INDOL-3-YL)-1,1-DIMETHYLETHYLAMINO]PROPOXY]BENZONITRILE
2-(2-hydroxy-3-((2-(1h-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)benzonitr
2-[2-Hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]benzonitrile
Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl)amino)propoxy)- | [Molecular Formula]
C22H25N3O2 | [MDL Number]
MFCD00865898 | [MOL File]
71119-11-4.mol | [Molecular Weight]
363.45 |
| Chemical Properties | Back Directory | [Melting point ]
125-127° | [Boiling point ]
605.3±55.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
Store at +4°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.76±0.20(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Antihypertensive. | [Biological Activity]
Non-selective β -adrenoceptor antagonist with additional α 1 -adrenoceptor blocking activity. K i values are 1.61, 1.20 and 68.9 nM for β 1 -, β 2 - and α 1 -adrenoceptors respectively. Also acts as a weak 5-HT 2A/2B antagonist. Displays vasodilatory and antihypertensive actions. | [storage]
Store at -20°C |
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