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ChemicalBook--->CAS DataBase List--->709641-79-2

709641-79-2

709641-79-2 Structure

709641-79-2 Structure
IdentificationBack Directory
[Name]

(E)-N'-{9-[(1R,3R,4R,7S)-1-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-7-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-N,N-dimethylmethanimidamide
[CAS]

709641-79-2
[Synonyms]

LNA-N-dmf Guanosine? Amidite
LNA-guanosine 3'-CE phosphoramidite
LNA-guanosine 3'-CE phosphoramidite
2'-O-4'-C-Locked-rG(dmf) Phosphoramidite
DMTr-2'-O-4'-C-Locked-rG(dmf)-3'-CE-Phosphoramidite
(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-(((dimethylamino)methylene)amino)-6-oxo-3H-purin-9(6H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
(1R,3R,4R,7S)-1-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(2-(((dimethylamino)methylene)amino)-6-oxo-3,6-dihydro-9H-purin-9-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
Methanimidamide, N'-[9-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-α-L-lyxofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-N,N-dimethyl- (9CI)
(E)-N'-{9-[(1R,3R,4R,7S)-1-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-7-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-N,N-dimethylmethanimidamide
(E)-N'-{9-[(1R,3R,4R,7S)-1-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-7-({[bis(propan-2-yl)amino](2-cyanoethoxy)phosphanyl}oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-N,N-dimethylmethanimidamide
[EINECS(EC#)]

633-043-4
[Molecular Formula]

C44H53N8O8P
[MDL Number]

MFCD30475595
[MOL File]

709641-79-2.mol
[Molecular Weight]

852.91
Chemical PropertiesBack Directory
[Boiling point ]

894.1±75.0 °C(Predicted)
[pka]

3.70±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

LNA-Guanosine 3'-CE phosphoramidite (Lna-g amidite) is an essential building block to Locked Nucleic Acid (LNA) oligonucleotide synthesis, which includes a ribonucleoside linked by a methylene unit between the 2’-oxygen and 4’-carbon atoms, paralleling DNA polymer assembly.
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