| Identification | Back Directory | [Name]
5-Ethynyl uridine | [CAS]
69075-42-9 | [Synonyms]
5-EU
5-Ethynyl uridine
Uridine, 5-ethynyl-
5-Ethynyl Uridine (EU)
5-Ethynyluridine (5-EU)
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpy
5-ETHYNYL URIDINE; 1-((2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-5-ETHYNYLPY
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione | [EINECS(EC#)]
500-100-4 | [Molecular Formula]
C11H12N2O6 | [MDL Number]
MFCD00876719 | [MOL File]
69075-42-9.mol | [Molecular Weight]
268.22 |
| Chemical Properties | Back Directory | [Melting point ]
>164oC (dec.) | [density ]
1.67±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO (Slightly), Methanol (Very Slightly, Heated, Sonicated) | [form ]
Solid | [pka]
8.29±0.10(Predicted) | [color ]
Off-White to Pale Beige |
| Hazard Information | Back Directory | [Description]
5-Ethynyl uridine (5-EU) is an alkyne-containing metabolic labeling reagent used to detect global RNA transcription temporally and spatially in both in-vitro and in-vivo with the modified nucleotide. The alkyne handler can be used for subsequent ligation to azide-containing molecules through a highly efficient click chemistry reaction. | [Uses]
5-Ethynyluridine is used to help detect RNA synthesis in cells by its biosynthetic incorporation into newly transcribed RNA. | [reaction suitability]
reaction type: click chemistry | [storage]
Store at -20°C |
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