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ChemicalBook--->CAS DataBase List--->68422-00-4

68422-00-4

68422-00-4 Structure

68422-00-4 Structure
IdentificationBack Directory
[Name]

Sarsasapogenin 3-O-β-D-galactopyranosid
[CAS]

68422-00-4
[Synonyms]

TiMosaponin A1
Timosaponin AI
Sarsasapogenin 3-O-β-D-galactopyranosid
Sarsasapogenin 3-O-β-D-galactopyranoside
β-D-Galactopyranoside, (3β,5β,25S)-spirostan-3-yl
Sarsasapogenin 3-O-β-D-galactopyranosid USP/EP/BP
[Molecular Formula]

C33H54O8
[MDL Number]

MFCD31706225
[MOL File]

68422-00-4.mol
[Molecular Weight]

578.79
Chemical PropertiesBack Directory
[Boiling point ]

695.5±55.0 °C(Predicted)
[density ]

1.26±0.1 g/cm3 (20 ºC 760 Torr)
[solubility ]

DMSO: 10 mM
[form ]

A solid
[pka]

12.91±0.70(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Timosaponin A1 exhibits a wide spectrum of bioactivities. Also, it is a metabolite of Timosaponin A3 (T444695), which suppresses certain human tumor processes and has the potential to be developed as an anticancer agent. Reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway. Induction of mitochondrial-dependent apoptosis in HepG2 human hepatocellular carcinoma cells.Timosaponin A3 is a potent inhibitor of U46619, that induces rat platelet aggregation and exhibited superior selectivity for the TP receptor vs. other G protein-coupled receptors and a PKC activator.
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