| Identification | Back Directory | [Name]
BEPRIDIL HYDROCHLORIDE | [CAS]
68099-86-5 | [Synonyms]
cordium
áüμ￡¨1￡
1978cerm
Bepricor
Einecs 268-472-2
EPRIDIL HYDROCHLORIDE
1-ISOBUTOXY-2-PYRROLIDINO-3-(N-BENZYLANILINO)PROPANE HCL
N-benzyl-beta-[(2-methylpropoxy)methyl]-N-phenylpyrrolidine-1-ethylamine monohydrochloride
BETA-[(2-METHYLPROPOXY)METHYL]-N-PHENYL-N-(PHENYLMETHYL)-1-PYRROLIDINE-ETHANAMINE HYDROCHLORIDE
β-[(2-methylpropoxy)methyl]-N-phenyl-N-(phenylmethyl)-1-pyrrolidineethanamine, monohydrochloride
1-Pyrrolidineethanamine, beta-((2-methylpropoxy)methyl)-N-phenyl-N-(phenylmethyl)-, monohydrochloride | [EINECS(EC#)]
268-472-2 | [Molecular Formula]
C24H35ClN2O | [MDL Number]
MFCD00065498 | [MOL File]
68099-86-5.mol | [Molecular Weight]
403 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO:59.08(Max Conc. mg/mL);147.34(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);49.88(Max Conc. mM)
Ethanol:25.0(Max Conc. mg/mL);62.35(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.75(Max Conc. mM) | [form ]
powder
| [color ]
white
|
| Hazard Information | Back Directory | [Uses]
Bepridil Hydrochloride is a calcium channel blocker. It also activates mitochondrial ATP-sensitive KATP channelsBepridil Hydrochloride is an antiarrhythmic and antihypertensive agent and used for treating atrial fibrillation. | [Definition]
ChEBI: The hydrochloride of bepridil. | [Biological Activity]
Non-selective calcium channel blocker and class IV antiarrhythmic agent; inhibits Na+-Ca2+ exchange; inhibits growth of brain tumor cells in vitro. | [in vivo]
Bepridil hydrochloride (21 mg/kg) reduces heart rate and mean arterial pressure, decreases the mean coronary vascular resistance and increases stroke volume in rats[1]. | [storage]
Desiccate at RT |
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