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ChemicalBook--->CAS DataBase List--->67920-52-9

67920-52-9

67920-52-9 Structure

67920-52-9 Structure
IdentificationBack Directory
[Name]

Sodium danshensu
[CAS]

67920-52-9
[Synonyms]

dium danshensu
Sodium danshensu
DANSHENSU SODIUM (RG)
Salvianic acid A sodium
(±)-DanShenSu sodium sal
Salvia natriuretic peptide
Sodium Danshensu 67920-52-9
Salvianic acid A sodium,HPLC≥98%
Sodium 3-(3,4-dihydroxyphenyl)lactate
Sodium 3-(3,4-dihydroxyphenyl)-DL-lactate
sodium D-(+)-β-(3,4-dihydroxyphenyl)lactate
Sodium DL-beta-(3,4-dihydroxyphenyl)lactate
3-(3',4'-Dihydroxyphenyl)lactic acid sodium salt
α,3,4-Trihydroxybenzenepropanoic acid sodium salt
sodium 3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate
3,4-Dihydroxyphenyl-α-hydroxypropanoic acid sodium salt
Benzenepropanoic acid, a,3,4-trihydroxy-, sodium salt(1:1)
3,4-Dihydroxyphenyl-.alpha.-hydroxypropanoic acid sodiuM salt
Sodium 3-(3,4-dihydroxyphenyl)lactate, 98%, from Salvia miltiorrhiza Bge.
[EINECS(EC#)]

804-287-0
[Molecular Formula]

C9H9O5.Na
[MDL Number]

MFCD09037393
[MOL File]

67920-52-9.mol
[Molecular Weight]

220.155
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

H2O : 100 mg/mL (454.24 mM; Need ultrasonic)DMSO : 100 mg/mL (454.24 mM; Need ultrasonic)
[form ]

powder
[color ]

White-beige
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22
[Safety Statements ]

24/25
[HS Code ]

29329990
Hazard InformationBack Directory
[Description]

Danshensu is a salvianolic acid and the major component of S. miltiorrhiza (Danshen) and has diverse biological activities. It reduces expression of the autophagy-associated proteins p62, LC3-II, and Beclin-1 and the apoptosis-related proteins Bax and caspase-3, prevents cardiomyocyte damage, and increases heart rate, coronary flow (CF), and left ventricular developed pressure (LVDP) in an isolated rat heart model of ischemia and reperfusion injury. Danshensu (60 mg/kg per day) reduces infarct size and improves left ventricular function in a rat model of myocardial infarction. It enhances radiation-induced tumor cell death in a Lewis lung carcinoma mouse xenograft model. Danshensu also decreases infarct volume, neuronal apoptosis, production of TNF-α, IL-1β, and IL-6, and superoxide dismutase (SOD) and glutathione peroxidase (GPx) activity in a rat model of cerebral ischemia and reperfusion injury.
[Chemical Properties]

White to light brown powder
[Uses]

Sodium Danshensu is exhibits protective effects on the excitotoxicity of monosodium glutamate in the late stage of pregnancy on developing mouse fetal brain.
[target]

Calcium Channel | Potassium Channel | Akt | GSK-3 | Bcl-2/Bax | PI3K
Spectrum DetailBack Directory
[Spectrum Detail]

Sodium danshensu(67920-52-9)1HNMR
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