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ChemicalBook--->CAS DataBase List--->65373-29-7

65373-29-7

65373-29-7 Structure

65373-29-7 Structure
IdentificationBack Directory
[Name]

5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE
[CAS]

65373-29-7
[Synonyms]

MS21570
ZERENEX E/5111275
5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE
N-(5-benzylsulfanyl-[1,3,4]thiadiazol-2-yl)-methylamine
1,3,4-thiadiazol-2-amine, N-methyl-5-[(phenylmethyl)thio]-
N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine
[Molecular Formula]

C10H11N3S2
[MDL Number]

MFCD01018163
[MOL File]

65373-29-7.mol
[Molecular Weight]

237.34
Chemical PropertiesBack Directory
[Boiling point ]

389.6±35.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 125 mg/mL (526.67 mM)
[form ]

Solid
[pka]

2.67±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[HazardClass ]

IRRITANT
Hazard InformationBack Directory
[Uses]

MS 21570, is a GPR171 antagonist. It reduces anxiety-like behavior and fear conditioning in mice.
[Biological Activity]

MS0021570 is a potent antagonist of GPR171a G protein-coupled receptor of BigLEN (b-LEN)which is a neuropeptide derived from proSAAS and involved in regulation of feeding. MS0021570 had a IC50 value of 220 nM. It was shown to block inceases in food intake and to reduce anxiety-like behavior and fear conditioning in mice.
[storage]

Store at -20°C
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