天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook--->CAS DataBase List--->65193-87-5

65193-87-5

65193-87-5 Structure

65193-87-5 Structure
IdentificationBack Directory
[Name]

3-Bromopropionaldehydedimethylacetal
[CAS]

65193-87-5
[Synonyms]

2-Cyanoethylacetoacetate
2-Cyanoethyl 3-Oxobutyrate
Butanoic acid, 3-oxo-,2-cyanoethyl ester
3-Bromopropionaldehydedimethylacetal 65193-87-5
[EINECS(EC#)]

613-755-1
[Molecular Formula]

C7H9NO3
[MDL Number]

MFCD24687999
[MOL File]

65193-87-5.mol
[Molecular Weight]

155.15
Chemical PropertiesBack Directory
[Boiling point ]

288.2±20.0 °C(Predicted)
[density ]

1.123±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Store in freezer, under -20°C
[pka]

10.04±0.46(Predicted)
[InChI]

InChI=1S/C7H9NO3/c1-6(9)5-7(10)11-4-2-3-8/h2,4-5H2,1H3
[InChIKey]

SWJVFAOGXDGTCX-UHFFFAOYSA-N
[SMILES]

C(OCCC#N)(=O)CC(=O)C
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H317-H319
[Precautionary statements ]

P280-P305+P351+P338
Hazard InformationBack Directory
[Chemical Properties]

Yellow to brown liquid.
[Uses]

2-Cyanoethyl Acetoacetate is an intermediate in the synthesis of Felodipine-d3 (F232377), a labelled dihydropyridine calcium channel blocker.
[Application]

2-Cyanoethyl 3-oxobutanoate is a diazepine that has been shown to have cardiac effects. It is used as a drug substance in the synthesis of diazepinone, which is a nitrosable drug and an infarction agent. It has been shown to induce cardiac contractility by binding to the functional site on the beta-1 adrenergic receptor. This compound also acts as an inhibitor of lipase, which may be due to its similarity in structure to the pharmacophore for this enzyme.
[Synthesis]

Method 1: 1.1 Step 1) 2-cyanoethyl acetoacetate 2,2,6-Trimethyl-4H-1,3-dioxan-4-one (15.50 g, 109.0 mmol), 3-hydroxypropionitrile (7.75 g, 109 mmol) and o-xylene (20 mL)The reaction was carried out at 141 ° C for 2 hours. Cool to room temperature,The solvent was evaporated to give a pale yellow oil (16.63 g, 98.30%).Method 2: 29 That is accurately weighed 1.42g 10mmol of 2,2,6-trimethyl-1,3-dioxin-4-one -4H and 0.82mL Approximately 12mmol of 2-hydroxy-acetonitrile, dissolved in 10mL of ethylene and heated to 140-145 ° C, The reaction was refluxed for 1h, cooled to room temperature, the solvent was removed by rotary evaporation and the residue was purified by flash column chromatography pure Of Compound S711.4g, 90% yield.

2-Cyanoethyl 3-oxobutanoate

65193-87-5 suppliers list
Company Name: Xuchang Hengsheng Pharmaceutical Co., Ltd
Tel: +86-03745692999 +86-13569491380 , +86-13569491380
Website: www.xchsyy.com/
Company Name: Zison Pharmaceutical (Shandong) Co., Ltd.
Tel: +86-0086-531-88259693 +86-18660188356 , +86-18660188356
Website: https://www.zisonpharm.com/
Company Name: shandong perfect biotechnology co.ltd
Tel: +86-53169958659 +86-13153181156 , +86-13153181156
Website: http://www.sdperfect.com/about_e/id/1.html
Company Name: Hebei Junhua Import and Export Co., LTD
Tel: +86-18503288844 +86-18503288844 , +86-18503288844
Website: m.approvedhomemanagement.com/manufacturer/hebei-junhua-import-and-export-25443/
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512 , +86-19937530512
Website: https://www.tianfuchem.com/
Company Name: Jinan Carbotang Biotech Co.,Ltd.
Tel: +8615866703830 , +8615866703830
Website: http://m.approvedhomemanagement.com/ShowSupplierProductsList31189/0.htm
Company Name: Accela ChemBio Inc.
Tel: +1-858-6993322
Website: www.accelachem.com/
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-6139-8061 +86-86-13650506873 , +86-86-13650506873
Website: http://www.chemdad.com/
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com
Company Name: Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
Tel: +86-519-85525359 +86-15995072465 , +86-15995072465
Website: https://www.xuanmingchem.com
Company Name: Shanghai UCHEM Inc.
Tel: +862156762820 +86-13564624040 , +86-13564624040
Website: http://www.myuchem.com/
Company Name: ANHUI WITOP BIOTECH CO., LTD
Tel: +8615255079626 , +8615255079626
Website: m.approvedhomemanagement.com/showsupplierproductslist418627/0_en.htm
Company Name: Wuhan Fortuna Chemical Co., Ltd
Tel: +86-027-59207850
Website: www.fortunachem.com/
Company Name: changzhou huayang technology co., ltd
Tel: +8615250961469 , +8615250961469
Website: http://www.huayangchem.com/template/eabout.html
Company Name: Nanjing Hengbei Chemicals Co., Ltd.
Tel: +86-25-58393656
Website: www.hengbeichem.cn
Company Name: Shanghai Joiny Pharmaceutical Co.,LTD
Tel: +8613681955282 , +8613681955282
Website: en.joiny-pharma.com/
Company Name: Wuhan ShuEr Biology Technology Co.,Ltd
Tel: +86-15629032529 , +86-15629032529
Website: m.approvedhomemanagement.com/ShowSupplierProductsList1132105/0.htm
Company Name: SUZHOU SENFEIDA CHEMICAL CO.,LTD
Tel: +86-0512-83500002 +8615195660023 , +8615195660023
Website:
Tags:65193-87-5 Related Product Information
718-08-1 25895-60-7 39615-79-7