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ChemicalBook--->CAS DataBase List--->63775-95-1

63775-95-1

63775-95-1 Structure

63775-95-1 Structure
IdentificationBack Directory
[Name]

Cyclosporin B
[CAS]

63775-95-1
[Synonyms]

CYCLOSPORIN B
Ala2-cyclosporine
Antibiotic S 7481F2
Cyclosporin B (9CI)
Cyclosporin B, >=95%
Cyclosporine IMpurity-B
7-L-Alaninecyclosporine A
(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Ala-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)
Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alanyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]
[Molecular Formula]

C61H109N11O12
[MDL Number]

MFCD08062361
[MOL File]

63775-95-1.mol
[Molecular Weight]

1188.58
Chemical PropertiesBack Directory
[Appearance]

Amorphous White Solid
[Melting point ]

149-152°C
[alpha ]

D20 -238° (c = 0.62 in chloroform); D20 -168° (c = 0.56 in methanol)
[Boiling point ]

1289.7±65.0 °C(Predicted)
[density ]

1.019±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

13.32±0.70(Predicted)
[color ]

White to Pale Yellow
[InChIKey]

UCOQITKXMNKTKF-MHWLBTFJNA-N
Hazard InformationBack Directory
[Chemical Properties]

Amorphous White Solid
[Uses]

An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
[Uses]

Cyclosporin B is a minor analogue of the cyclosporin complex produced by a number of different fungal genera including Trichoderma, Tolypocladium, Fusarium, Nectria and Acremonium. Cyclosporin B possesses immunosuppressant and antifungal activities but has been much less extensively investigated than the major analogue, cyclosporin A.
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