| Identification | Back Directory | [Name]
Ginsenoside Rh1 | [CAS]
63223-86-9 | [Synonyms]
GINSENOSIDE RH1
Sanchinoside B2
gensenoside Rh1
Prosapogenin A2
sanchinoside rh1
(S)Ginsenoside-Rh1
GINSENOSIDE Rh1(SH)
Ginsenoside Rh1 ,98%
Ginsenoside Rh1 (Prosapogenin A2
Ginsenoside Rh1, 98%, from Panax ginseng C. A. Mey.
6α-(β-D-Glucopyranosyloxy)-dammara-24-ene-3β,12β,20-triol
(20S)-6α-(β-D-Glucopyranosyloxy)dammar-24-ene-3β,12β,20-triol
3β,12β,20-Trihydroxy-5α-dammar-24-en-6α-yl β-D-glucopyranoside
(20S)-6α-(β-D-Glucopyranosyloxy)-3β,12β,20-trihydroxydammara-24-ene
β-D-Glucopyranoside, (3β,6α,12β)-3,12,20-trihydroxydammar-24-en-6-yl
(3beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl?beta-d-glucopyranoside
(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]ph | [Molecular Formula]
C35H60O9 | [MDL Number]
MFCD02259430 | [MOL File]
63223-86-9.mol | [Molecular Weight]
624.85 |
| Chemical Properties | Back Directory | [Boiling point ]
755.1±60.0 °C(Predicted) | [density ]
1.23 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO : 100 mg/mL (156.53 mM; Need ultrasonic) | [form ]
powder | [pka]
12.91±0.70(Predicted) | [color ]
White | [LogP]
3.740 (est) |
| Hazard Information | Back Directory | [Uses]
20(S)?-?Ginsenoside Rh1 is an anti-cancer agent found in the leaves of ginseng. | [Definition]
ChEBI: (20S)-ginsenoside Rh1 is a tetracyclic triterpenoid that is (20S)-protopanaxadiol which is substituted by beta-D-glucoside at the 6alpha position. It has a role as a plant metabolite. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a tetracyclic triterpenoid, a ginsenoside, a 3beta-hydroxy steroid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane. | [in vivo]
When high-fat diet (HFD) fed mice for 8 weeks, body and epididymal fat weight gains are significantly increased compared to those of low-fat diet (LFD)-fed mice. However, when Ginsenoside Rh1 is treated in HFD-fed mice, body and epididymal fat weight gains are significantly decrease compared with those of the HFD-fed mice. TG, glucose, insulin, total cholesterol, and HDL levels in the blood are significantly increased in HFD-fed mice group compared to LFD-fed mice group. Treatment with Ginsenoside Rh1 in HFD-fed mice significantly lowers TG level alone[1]. | [IC 50]
PPAR-γ; IL-6; IL-1β |
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