| Identification | Back Directory | [Name]
OMDM-6 | [CAS]
616884-67-4 | [Synonyms]
OMDM-6
OMDM 6,OMDM6
5,8,11,14-Eicosatetraenoic acid, 2-[(4-hydroxy-3-methoxyphenyl)methyl]hydrazide, (5Z,8Z,11Z,14Z)- | [Molecular Formula]
C28H42N2O3 | [MDL Number]
MFCD34469998 | [MOL File]
616884-67-4.mol | [Molecular Weight]
454.66 |
| Hazard Information | Back Directory | [Uses]
OMDM-6 is a hybrid agonist of vanilloid receptor type 1 (VR1, TRPV1) (EC50=75 nM) and cannabinoid receptor type 1 (CB1) (Ki=3.2 μM). OMDM-6 inhibits anandamide cellular uptake (ACU) with a Ki of 7.0 μM[1]. | [References]
[1] Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65(9):1473-81. DOI:10.1016/s0006-2952(03)00109-6 |
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