| Identification | Back Directory | [Name]
Z-PRO-D-LEU-OH | [CAS]
61596-47-2 | [Synonyms]
Z-PL
Z-PRO-D-LEU
prolylleucine
Z-PRO-D-LEU-OH
Cbz-Pro-D-Leu-OH
Z-L-PROLYL-D-LEUCINE
MORPHINE TOLERANCE PEPTIDE
N-CARBOBENZOXY-L-PROPYL-D-LEUCINE
N-carbobenzyloxy-proline-D-leucine
((Benzyloxy)carbonyl)-L-prolyl-D-leucine
D-LEUCINE, 1-[(PHENYLMETHOXY)CARBONYL]-L-PROLYL-
D-Leucine, 1-[(phenylmethoxy)carbonyl]-L-prolyl- (9CI)
4-methyl-2-[[oxo-(1-phenylmethoxycarbonyl-2-pyrrolidinyl)methyl]amino]pentanoic acid | [Molecular Formula]
C19H26N2O5 | [MDL Number]
MFCD00020823 | [MOL File]
61596-47-2.mol | [Molecular Weight]
362.42 |
| Chemical Properties | Back Directory | [Boiling point ]
593.7±50.0 °C(Predicted) | [density ]
1.224±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.71±0.21(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Prolylleucine is a dipeptide containing branched-chain amino acids. Prolylleucine can affect the circadian rhythms and behaviour of animals[1][2]. | [References]
[1] Hebert EM, et al. Characterization of the pattern of alphas1- and beta-casein breakdown and release of a bioactive peptide by a cell envelope proteinase from Lactobacillus delbrueckii subsp. lactis CRL 581. Appl Environ Microbiol. 2008 Jun;74(12):3682-9. DOI:10.1128/AEM.00247-08
[2] E V Kravchenko, et al. Influence of changes in the state of brain neurotransmitter and peptidergic systems on circadian rhythms and behavior of rats. Zh Vyssh Nerv Deiat Im I P Pavlova. Jul-Aug 2012;62(4):453-64. PMID:23035562 |
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