| Identification | Back Directory | [Name]
FLUORESCEIN ISOTHIOCYANATE-DEXTRAN | [CAS]
60842-46-8 | [Synonyms]
FD 10S
FITC-Dextra
FITC-DEXTRAN
FITC I DEXTRAN
FLUORO-EMERALD
FITC-Dextran 4
FITC-Dextran 70
FITC-dextran 64
FITC-Dextran 150
FITC–Dextran 2000
FLUORESCEIN DEXTRAN
DEXTRAN, FLUORESCEIN
FITC-Dextran (4 kDa)
DEXTRAN, BODIPY(R) FL
FITC-Dextran (10 kDa)
FITC-Dextran (MW 4000)
FITC-dextran 4，Mw：4kDa
FITC-Dextran (MW 10000)
FITC-Dextran (MW 20000)
FITC-Dextran (MW 40000)
FITC-Dextran (MW 70000)
FITC-Dextran (MW 110000)
FITC-Dextran (MW 150000)
FITC-Dextran (MW 500000)
FITC-dextran 70，Mw：70kDa
FITC-dextran 20，Mw：20kDa
FITC-dextran 40，Mw：40kDa
FITC-dextran 10，Mw：10kDa
FITC-Dextran (MW 2000000)
FITC-dextran 500，Mw：500kDa
FITC-dextran 150，Mw：150kDa
FITC-dextran 110，Mw：110kDa
FITC-Dextran (MW 3000-5000)
FITC-dextran 2000，Mw：2000kDa
FLUORESCEIN ISOTHIOCYANATE-DEXTRAN
FLUORESCEIN ISOTHIOCYANATE I DEXTRAN
FITC-Dextran 4000 ex. Leuconostoc Sp.
FITC-Dextran 40000 ex. Leuconostoc Sp.
FITC-Dextran 70000 ex. Leuconostoc Sp.
FITC-Dextran 2000000 ex. Leuconostoc Sp.
FITC Dextran (MW 10000),FITCDextran (MW 10000)
Fluorescein isothiocyanate–dextran/FITC-dextran
FLUORESCEIN ISOTHIOCYANATE DEXTRAN 150000-CONJUGATE
Fluorescein Isothiocyanate Dextran (Mw.=ca. 10,000)
FLUORESCEIN ISOTHIOCYANATE DEXTRAN 5000000-CONJUGATE
Fluorescein isothiocyanate-dextran - Average MW 10,000
Fluorescein isothiocyanate-dextran - Average MW 20,000
Fluorescein isothiocyanate-dextran - Average MW 70,000
Fluorescein isothiocyanate-dextran average mol wt 20,000
Fluorescein isothiocyanate-dextran average mol wt 40,000
Fluorescein isothiocyanate-dextran average mol wt 10,000
Fluorescein isothiocyanate-dextran average mol wt 250,000
Fluorescein isothiocyanate-dextran average mol wt 500,000
Fluorescein isothiocyanate-dextran average mol wt 150,000
Fluorescein isothiocyanate-dextran average mol wt 2,000,000
Fluorescein isothiocyanate-dextran average Mw 59,000-77,000
Fluorescein isothiocyanate-dextran - Average MW 3,000-5,000
Fluorescein isothiocyanate-dextran average mol wt 3,000-5,000 | [MDL Number]
MFCD00131092 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C
| [solubility ]
H2O: 50 mg/mL, slightly hazy, orange
| [form ]
powder to crystaline | [color ]
Light yellow to Yellow to Orange | [biological source]
synthetic (organic) | [Water Solubility ]
water: 25mg/mL, cloudy to hazy, yellow to orange |
| Hazard Information | Back Directory | [Chemical Properties]
Dextran labeled with fluorescein isothiocyanate | [Uses]
water soluble cellulase substrate | [General Description]
Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran. Conflicting data on the branch lengths implies that the average branch length is less than three glucose units. However, other methods indicate branches of greater than 50 glucose units exist. Native dextran has been found to have a molecular weight (MW) in the range of 9 million to 500 million. Lower MW dextrans will exhibit slightly less branching and have a more narrow range of MW distribution. Dextrans with MW greater than 10,000 behave as if they are highly branched. As the MW increases, dextran molecules attain greater symmetry. Dextrans with MW of 2,000 to 10,000, exhibit the properties of an expandable coil. At MW below 2,000, dextran is more rod-like. The MW of dextran is measured by one or more of the following methods: low angle laser light scattering, size exclusion chromatography, copper-complexation and anthrone reagent colorometric reducing-end sugar determination and viscosity. | [Biological Activity]
FITC-Dextran serves as a versatile fluorescent tracer extensively used in biological and physiological research. Its primary actions encompass the assessment of permeability in biological barrierssuch as the blood-brain barriercell membranesand vascular walls. It is also utilized to investigate cellular uptake mechanismsendocytosisand cell junction permeabilityfocussing on essential cellular processes. FITC-Dextran aids in measuring blood flowvascular drainageand renal eliminationproviding insights into microcirculation and capillary dynamics. Furtherthis marker is also instrumental in understanding tissue and organ characteristics and can serve as a valuable tool for tracing moleculescontributing to the exploration of a wide array of biochemical phenomena. |
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