| Identification | Back Directory | [Name]
Tiazofurine | [CAS]
60084-10-8 | [Synonyms]
TCAR
CI 909
Riboxamide
NSC-286193
tiazofurin
Aids014479
Aids-014479
NSC-286-193
Tiazofurine
2-b-D-Ribofuranosyl-4-thiazolecarboxaMide
2-β-D-Ribofuranosyl-4-thiazolecarboxaMide
2-β-D-Ribofuranosylthiazole-4-carboxaMide
4-Thiazolecarboxamide, 2-β-D-ribofuranosyl-
2-.beta.-D-Ribofuranosyl-4-thiazolecarboxamide | [Molecular Formula]
C9H12N2O5S | [MDL Number]
MFCD00866494 | [MOL File]
60084-10-8.mol | [Molecular Weight]
260.27 |
| Chemical Properties | Back Directory | [Melting point ]
145-146° | [alpha ]
D25 -9° (c = 0.5 in ethanol) | [density ]
1.4797 (rough estimate) | [refractive index ]
1.6800 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly) | [form ]
Solid | [color ]
White to Pale Beige | [Stability:]
Very Very Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5'-monophosphate (IMP) dehydrogenase. | [Definition]
ChEBI: A C-glycosyl compound that is 1,3-thiazole-4-carboxamide in which the hydrogen at position 2 has been replaced by a beta-D-ribofuranosyl group. It is metabolised to thiazole-4-carboxamide adenine dinucle
tide (TAD), a selective inhibitor of inosine monophosphate dehydrogenase (IMP dehydrogenase). | [Brand name]
Tiazofurine is INN. | [storage]
Store at -20°C |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|