| Identification | Back Directory | [Name]
Glabrone | [CAS]
60008-02-8 | [Synonyms]
Glabrone
7-Hydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7-hydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)- | [Molecular Formula]
C20H16O5 | [MDL Number]
MFCD32197346 | [MOL File]
60008-02-8.mol | [Molecular Weight]
336.34 |
| Chemical Properties | Back Directory | [Boiling point ]
554.1±50.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
6.91±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Glabrone is an isoflavone isolated from Glycyrrhiza glabra roots. Glabrone exhibits anti-influenza activity and significant PPAR-γ ligand-binding activity[1][2]. | [Definition]
ChEBI: Glabrone is an isoflavonoid. | [IC 50]
PPAR-γ | [storage]
Store at -20°C | [References]
[1] Grienke U, et al. Computer-guided approach to access the anti-influenza activity of licorice constituents. J Nat Prod. 2014 Mar 28;77(3):563-70. DOI:10.1021/np400817j
[2] Kuroda M, et al. Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity. Bioorg Med Chem. 2010 Jan 15;18(2):962-70. DOI:10.1016/j.bmc.2009.11.027 |
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